Cocaine and Anxiety
Cocaine and anxiety...it is not clear how cocaine produces this anxiety effect, it is likely that it is produced by the release of large amounts of dopamine in the brain.
Cocaine also affects at least three parts of the brain itself:
the cerebral cortex, which governs reasoning and memory;
the hypothalamus, which controls appetite, body temperature, sleep,
and emotions such as fear and anger; and the cerebellum,
which regulates motor activities such as walking
and balance.
Like heroin, cocaine initially had a positive, even
benign impact, Freud, who periodically used cocaine
himself, recommended it for use in treating depression
and other conditions, including morphine withdrawal.
Its use as a local anesthetic led to the discovery of synthetic
substitutes with low toxicity, while its use in
treating morphine withdrawal indirectly led to self-administration
of the drug. From about 1880 to 1900 cocaine
was actually an ingredient in some popular brands
of soda pop.
Cocaine can be "snorted" or sniffed, smoked (often
in a water pipe), or injected directly. Today cocaine
is the drug of choice for many conventional and often
upwardly mobile citizens-young professionals, executives,
politicians-and is used rather openly in spite of
its illegal status.
It produces feelings of wittiness and hyper
alertness and is often praised by
users as being almost risk free: no hangovers like those
produced by alcohol, no injection scars like those caused
by heroin use, and no lung cancer, which is associated
with use of marijuana and tobacco . Unfortunately, its
action is more complex and less benign than most users
believe. I’ve listed the effects of cocaine use.
High doses or repeated use of cocaine can produce
a state resembling mania, with impaired judgment, incessant
rambling talk, hyperactivity, and paranoia that
may lead to violence or accidents. There is also an acute
anxiety reaction that is sometimes severe enough to be
called panic. Serious acute physical reactions are also
possible. By restricting blood vessels and increasing
“Effects of Cocaine"
1. Euphoria
2. Increased energy
3. Enhanced mental acuity and alertness
4. Increased sensory awareness (sexual, auditory, visual)
5. Decreased appetite
6. Decreased need for sleep
7. Increased self-confidence
8. Delusions
10. Convulsions
11. Anxiety
The effects depend on dosage and degree of habitual use.
Increased heart rate, cocaine can produce cardiac symptoms,
including irregular heartbeat, angina, and myocardial infarction.
High doses may also cause nausea, headache,
cold sweats, tremors, and fast, irregular, shallow breathing.
People who have high blood pressure or damaged
arteries may suffer strokes as a result of cocaine use.
Death usually results from convulsions followed by paralysis
of the brain centers controlling respiration, followed
by cardiac arrest; in serious cases an-acute overdose
must be treat with and anti-convulsant drugs.
A common cause of death is intravenous injection a
"speedball"-a combination of heroin and cocaine.
Cocaine presents serious problems when it is taken
habitually in large doses. As long as only a limited quantity
is consumed, cocaine can be taken daily for, years
with no apparent ill effects. But since it is one of the
most powerful drug reinforces, desire for it is hard to
control. A damaging habit usually develops over a period
of several months to several years. Compulsive
users cannot turn the drug down; they think about it
constantly, dream about it, spend all their savings on it,
steal, or deal to pay for it.
Long-term tolerance for cocaine develops very fast
with repeated doses during a single session;
lowed by crashes.
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